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Plexus Triplex Review: Could you lose weight with this friendly bacteria trio?



Plexus SlimPlexus Triplex is a trio of weight control supplements from Plexus focused around improving digestive health to achieve your goals.

Based upon the ethos: restore, remove and rebalance, these three products Plexus Biocleanse, Plexus Slim and Plexus Probio 5 are designed to work in unison.

Plexus Triplex contains multiple ingredients which promote the growth of gut-friendly bacteria and metabolism enhancing microbes to help with weight loss.


What is Plexus Triplex?

Plexus Triplex is a weight management system comprising of three different supplements. It targets support of the digestive system to improve health and encourage weight loss.

How to take Plexus Triplex?

Plexus Triplex is a three-part system consisting of ‘Plexus Bio Cleanse’, ‘Plexus Slim’, and ‘Plexus Pro Bio 5’. Two capsules of Bio Cleanse should be taken twice a day between main meals with an 8 oz glass of water. Slim should be drunk 30-60 mins prior to meals up to twice a day. 1-2 capsules of Pro Bio 5 should be taken before bedtime.

Who should use Plexus Triplex?

Plexus Triplex should be used by those who are looking to improve their digestive and overall health as well as lose some weight.

How much does Plexus cost per month?

Plexus Triplex costs $149.95 per month. If you get a subscription you receive a discounted price of $129.95.  

Is Plexus Triplex safe?

The ingredients in Plexus Triplex are natural and are not controlled substances. Plexus Triplex should be safe to use so long as you take according to the directions. If you are sensitive to caffeine you may experience some side effects from taking this product.

Is Plexus Triplex legal?

Yes, Plexus Triplex is legal.

Where to buy Plexus Triplex?

You can purchase Plexus Triplex from their official website and also from Amazon.

Do they ship Plexus Triplex worldwide?

Plexus Triplex is available in the USA, Canada, Australia and New Zealand.

Does Plexus Triplex really work?

The ingredients in Plexus Triplex have been clinically proven to have a beneficial effect upon gut health and also weight loss.

How long do you have to take Plexus Triplex before seeing results?

Results will inevitably vary among individuals. Plexus Triplex comes in a month by month supply. If taken correctly in combination with a healthy diet and exercise you could see results within a month.


Plexus Triplex believes there is more to health than just weight loss. Their supplement system aims to improve the health of the body both inside and out.

The primary benefits of Plexus Triplex are as follows:

Gut Health

Plexus Biocleanse works to cleanse the gastrointestinal tract, reducing the effect of any issues such as bloating, gas, and abdominal discomfort.

The supplement has a detoxifying effect that works to eliminate any bad bacteria that may be lingering in the gut.

Plexus Probio5 helps to maintain the balance of yeast levels in the gut to promote digestive health.

It supports healthy digestion and improves the PH level of the gut.

Weight Loss

Plexus Slim is a fat burner for women to help users lose weight by promoting the growth of beneficial microbes in the gut. Specifically, microbes lactobacillus and bifidobacterium.

The microbes Lactobacillus and bifidobacterium have been proven to improve digestive health. (1, 2)

Plexus Slim also claims to boost the metabolism by enhancing levels of akkermansia microbes. These microbes are linked to lower levels of obesity. (3)

Alongside metabolism boosting microbes, Plexus Slim contains garcinia cambogia which is known to help assist with weight loss.

Body Detox

In everyday life we are constantly exposed to toxins – environmental pollution or food based pesticides are just two perfect examples. (4)

When we take in these harmful substances they absorb into the body and start to build up. As they accumulate it also creates a greater risk of health problems, including weight gain.  

Detoxification can be simply defined as flushing out the bad stuff from your body.

The liver is what you would call your natural detox system.

It’s constantly working to process all the harmful substances to make sure they are removed or transformed into a friendlier alternative. (5)

However, there are times when the body gets overloaded and it just can’t cope with the workload which means a cleanse is in order.

Plexus Triplex aims to support the body’s natural detox system so that toxins are removed and healthy balance is regained.


The Plexus Triplex supplements are made using vitamins, minerals and various blends of antioxidants, enzymes and probiotics. Here are the highlights:

Garcinia Cambogia

Garcinia Cambogia is a  fruit that is mainly found in tropical areas across Asia.

Clinical trials have shown HCA inhibits the production of fat in your body by restricting the action of the enzyme citrate lyase. (6)

This fruit has also been proven to help suppress your appetite. (7)


An essential element in the human body, chromium is important for the regulation of insulin and blood sugar levels. (8)

Chromium can reduce the appetite and make you feel full when eating less.

This is especially helpful for those who are on a calorie restricted diet.

Green Coffee Bean

Green coffee beans are very high in caffeine, which is a well known stimulant. It has proven effects upon boosting the metabolism. (9)

Caffeine boosts energy and is great for improving athletic performance and training. It is also often used to sharpen the mind and assist with focus. (10)

Some clinical studies have shown that caffeine supplementation can accelerate the breakdown and burning of body fat. (11)


Magnesium is a dietary mineral which is very important to many functions in the human body.

Deficiency in magnesium is a worsening problem, with more and more people in the USA not getting enough magnesium in their diets. (12)

Magnesium plays a role in the processes which affect the functioning of the muscles. There is even evidence that a marginal magnesium deficiency can have a negative impact on energy and exercise performance. (13)


Plexus Triplex contains a combination of the digestive enzymes like protease, cellulase, chitosanase and serrapeptase.

Enzymes are critical to digestive health. They are important to support the breakdown of proteins, carbohydrates and fats and the absorption of these nutrients in the gut. (14)

Making sure your body is getting the nutrition it needs can contribute to an increase energy levels. This is very useful if you are trying to stick to an new workout regime.


Lactobacillus is commonly found in fermented food products aimed at promoting a healthy stomach with its probiotic action. 

Lactobacillus attacks bad bacteria in the gut, making sure the delicate balance remains stable within the digestive system. (15)

When your stomach has the right balance between good and bad bacteria it helps to improve health and energy levels. (16)

Alpha Lipoic Acid

Alpha lipoic acid is a compound that helps boost metabolism. (17)

This means, ALA has been found to help burn more calories. (18)

Supplementation with alpha lipoic acid can help to aid weight loss. (19)

Side Effects

Most of the ingredients in Plexus Triplex are of natural origin and designed to support your body.

This usually indicates a lower chance of side effects, but that doesn’t mean it’s completely risk free.  

Potential side effects of Plexus Triplex mainly relate to digestive issues such as: gas, constipation, stomach ache and nausea.

It is important to note that Plexus Triplex also contains caffeine (from the green coffee bean). If you are sensitive to caffeine you may experience anxiety, insomnia, headaches, dizziness or a ‘jittery’ feeling.

If any of these side effects become bothersome, stop taking Plexus Triplex and consult your physician before continuing.

Recommended Dosage

Because Plexus Triplex is made up of three different supplements, it is important you take them all correctly for best results.

Plexus Bio Cleanse

Take two capsules of Bio Cleanse twice a day with 8 oz of water (a full glass will do).

It is recommended that you take two capsules between breakfast and lunch, then another two between lunch and dinner.

Plexus Slim

Plexus Slim is a powder based drink. Mix the packet contents with 12-20 oz of water, shake well and then drink 30-60 mins before your meal. You can take 1-2 times per day.

Plexus Pro Bio 5

Take 1-2 capsules at bedtime on a empty stomach.


Plexus Triplex takes a different approach to weight loss with additional benefits towards all round health too.

Many of the ingredients in Plexus Triplex have been clinically proven to have beneficial effects upon gut health and fat loss.

However, the usage directions can seem quite involved which doesn’t make it the most straightforward supplement regime to follow. Furthermore, the digestive related side effects such as gas or bloating could also some people off.

The point to take home is Plexus Triplex has the potential to improve your health even if it doesn’t lead to weight loss.

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