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LA-3 review: is it the solution for longevity?



LA-3 review

LA-3 is a dietary supplement which uses new biotechnology to help boost your energy levels whilst promoting a stronger and healthier body.

The formula is based around activating an enzyme found in the body called ‘AMPK’ . LA-3 pledges to promote healthy ageing, increase lifespan, reduce fatigue and increase energy with the added bonus of a  a slimmer waistline.

The intent of this LA-3 review is to really get inside as to whether it effectively improves both your physical and mental well-being whilst increasing longevity.


What is LA-3?

LA-3 is a dietary supplement designed to boost energy levels, encourage clear thinking, reduce abdominal fat and promote a stronger, healthier body.

How does LA-3 work?

LA-3 works by enhancing AMPK levels in your body.AMPK promotes healthy ageing, weight loss and increased energy.

Who should use LA-3?

Due to the natural origin of its active ingredients in LA-3, it’s generally safe and effective for all adults who are looking for a boost. However, it’s not suitable for pregnant women.

How much does LA-3 cost?

For a 30 day supply, LA-3 will cost you $46.99.

Is LA-3 a fad?

No. Unlike a fad diet LA-3 does not promise a quick fix solution for weight loss or health enhancement. LA-3 simply combines naturally occurring ingredients to help you with weight loss and provide you with a natural energy boost.

Is LA-3 safe?

Yes. LA-3 contains no synthetic additives, no dairy and no caffeine. LA-3 is tested by a third party for safety and purity.

Where to buy LA-3?

LA-3 can be bought online either from the official website or from online retailers such as Amazon.

Does LA-3 really work?

The active ingredients in LA-3 have been clinically proven for their  positive impacts on longevity, weight loss and enhanced energy. (22,23,24)

Are there LA-3 alternatives?

There are various other dietary supplements on the market which claim to provide similar results as LA-3: Life Extension’s AMPK Metabolic Activator, Tru Niagen and Divine Bounty Berberine supplements.


LA-3 is engineered to boost energy enzymes, longevity and provide you with multiple health benefits for both the mind and the body.

Here we will look at the benefits of LA-3 in finer detail:

Boosts Energy Levels

Feelings of lethargy and tiredness can be problematic obstacles when it comes down to productivity, healthy living and creativity.

It’s a struggle to feel and do our best when we’re lacking lustre. We need both mental and physical energy for motivation, inspiration and enthusiasm.

LA-3 contains ingredients which intend to address this issue.

AMPK, is activated by a low energy supply and works to regulate and increase energy levels in the body. (1)

Greater energy levels have various positive effects on our health. When we have vitality we become more active, happier and less agitated.

Increased energy supports a healthy immune system, weight loss, and increases sleep.

Clearer Thinking

We all need to be able to think clearly in order to problem solve, rationalise and focus. It’s a vital tool for living a healthy and happy life.

However, when the body is unable to use energy effectively, our mind also suffers.

Glucose is the main source of fuel for our bodies and it also has a close relationship with cognitive performance. A lack of energy caused by low glucose levels can lead to ‘brain fog’ which hinders memory and concentration. (2)

LA-3 claims to improve insulin response in the body and help subdue sugar cravings. Studies show that this aids with forgetfulness and improves the ability to perform tasks requiring high levels of reasoning skills. (3)

Decreased Abdominal Fat

Excessive abdominal fat is a major culprit for contributing to heart disease, type 2 diabetes, insulin resistance and even some cancers. (4)

Abdominal fat is often a target area for those wishing to lose weight and tone up, but unfortunately it is also notoriously the most stubborn type of fat to shift.

Just like many parts of the body, fat residing in the abdominal area is a storage center for energy.

LA-3 activates and engages the enzyme which tells your body to stop storing fat and instead start converting it into energy. Therefore by regulating energy management in the body, LA-3 claims to help you banish abdominal fat.

Reducing abdominal fat contributes to the overall reduction of body fat and helps achieve weight loss.

Stronger, Healthier Body

We take care of our bodies by working out at the gym and regulating our diet. We do this so we can be strong, fit and healthy. We invest in ourselves, our body,  health and strength.

We should not therefore neglect the importance of biological chemicals and enzymes in the brain and body which contribute to overall good health.

LA-3 make this a lot easier by combing 3 active ingredients which work to activate significant compounds within our bodies.

LA-3 has proven anti-inflammatory and anti-allergen properties as well as helping to reduce blood sugar levels. These health benefits contribute to an overall healthier and stronger body. (5, 6)


LA-3 is a formula containing 3 natural ingredients: gynostemma, berberine and quercetin. We will now look at the science behind them.

Gynostemma Pentaphyllum Leaf Extract (ActivAMP)

Gynostemma is a member of the ginseng family. It’s an adaptogenic herb found in South and East Asia. The compounds or ‘sestrins’ found in its leaf extract activate the enzyme called AMPK.

AMPK  is often referred to as the ‘master metabolic regulator’ due to it engaging the same fat burning and energy releasing metabolic processes as exercise. (7)

AMPK is a central regulator of energy homeostasis which manages metabolic pathways, therefore balancing nutrient supply and energy demand. (8)

This body substance is touted as the key enzyme for perpetual youthful energy. It also naturally depletes during our ageing process. (9)

Studies have proven gynostemma pentaphyllum extract to be a potent anti-obesity substance. (10)  


Quercetin is a chemical found in many fruits and vegetables such as tomatoes, berries, broccoli and leafy greens that has numerous health benefits including antioxidant properties. (11)

Quercetin contributes to a stronger and healthier body.

It has been clinically shown to produce anti-inflammatory and anti-allergy effects in the body by preventing the production of cells which promote inflammation. (12)

Studies show that quercetin can help obesity by improving insulin sensitivity in the body. This can help with weight loss. (13)

Quercetin boosts energy levels.

Unknown to many people, Inflammation is linked with fatigue and low energy levels. Not the type of inflammation that occurs due to a sprained ankle but ‘chronic’ inflammation which is relatively mild and found throughout the whole body. (14)

Clinical research shows that this type of chronic inflammation reduces energy and increases fatigue by altering central nervous system activity. (15)

Therefore due to its anti-inflammatory properties quercetin enhances energy levels and supports clear thinking.


Berberine is a chemical found naturally occurring in many plants. Berberine has gained growing attention in recent years for its vast beneficial biological effects on the body.

Berberine is antibacterial and improves gut health.

Studies have found that berberine, like quercetin, works to reduce inflammation. (16)

Another great benefit of berberine is that it effectively regulates blood sugar levels. A healthy blood sugar level is key for overall fitness and for supporting your body to convert stored fat (including abdominal) into energy. (17)

Berberine is also known to have favourable cognitive effects and is an effective supplement because it can easily pass through the blood-brain barrier. (18)

Studies show that berberine has cognitive enhancing properties. (19)

By reducing neuroinflammation berberine works as a neuroprotector. These benefits strengthen learning and memory ability in the brain. (20)

Side Effects

The active ingredients in LA-3 are all naturally occurring nutrients found not only in food products but in our own bodies. This means LA-3 is safe to use however the ingredients in LA-3 may produce side effects.

Potential side effects of gynostemma pentaphyllum includes severe nausea and irritated bowel movements. Gynostemma pentaphyllum has also been proven to slow blood clotting. (21)

Quercetin can cause headaches and a tingling sensation in the arms and legs.

The common side effects of berberine are linked with digestion. This includes stomach cramps and pain, constipation, excessive gas and diarrhea.

Recommended Dosage

Directions for LA-3 are straightforward, you just need to take 2 capsules per day. These can be taken  with or without food.


LA-3 Is geared to boost energy, help you slim down your waistline and promotes longevity.

However, despite a plethora of clinical research highlighting the medical benefits of the individual ingredients of LA-3, there isn’t really any proof that the combined supplement is itself effective.

It’s good to see LA-3 does not hide behind a proprietary blend and instead very clearly indicates the ingredients and amounts. This means you know exactly what you are taking.

Overall, LA-3 could be a great way to aid weight loss and increase energy. However this can only be achieved by a balanced diet and fit and active lifestyle – which the LA-3 website fails to mention.

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